Discover your customized skincare routine.

Skincare is a journey, and Biologique Recherche Products are our trusted skincare companions. Let our Biologique experts guide you to beautiful skin. Experience the pure and practical power of Biologique Recherche skincare products from France, designed to avoid allergic and adverse reactions. Please fill out our skin analysis form using the button below to receive personalized product recommendations from our experts tailored to your skin type and concerns. Biologique Recherche from France delivers unrivaled results with scientifically formulated products that use the purest ingredients containing high concentrations of all-natural botanical, biological, and marine extracts.

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What are Biologique Recherche products?

Biologique Recherche products are the culmination of decades of cutting-edge research and innovation in skincare. These premium skincare solutions are renowned for their exceptional quality and efficacy, formulated with a meticulous blend of natural ingredients and advanced biotechnological compounds. With a focus on personalized regimens and a holistic approach to skincare, Biologique Recherche offers a comprehensive range of products designed to address various skin concerns, from hydration and rejuvenation to brightening and firming. Elevate your skincare routine with these luxurious and results-driven formulations backed by a legacy of excellence in beauty and wellness.

Biologique Recherche Facials at Lorena Luca

State-of-the-art skincare tailored to your skin's needs. Enhance the effectiveness of your Biologique Recherche skincare routine with one of our indulgent Biologique Recherche Facials for truly remarkable results.

Call or text us to speak with one of our Biologique Recherche experts.

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Our cleansing milk effectively eliminates all makeup and environmental pollutants. Apply them with gentle, upward, and outward massaging motions, starting from the neck and moving towards the forehead, to cleanse the skin of impurities. Afterward, use a moistened cotton pad to rinse away the cleansing milk, leaving your skin refreshed and rejuvenated. The active ingredients kickstart the beauty treatment, leaving the skin feeling soft and revitalized. These products serve as the initial step in every Biologique Recherche beauty care regimen and are incorporated into the daily skincare routine, both morning and night. Makeup removal should begin on the eye area using a clean cotton pad.

Eau Micellaire Biosensible Soothing Micellar Water

Eau Micellaire Biosensible Soothing Micellar Water for the Face

Eau Micellaire Biosensible combines moisturizing, toning, and soothing properties to effectively and gently remove makeup and impurities without destabilizing the skin's hydrolipidic film.

Lait E.V.

Lait E.V.

This milky cleanser purifies the skin without stripping protective oils. Vitamins A and F plump and moisturize while helping smooth the complexion. Skin is instantly soft and completely clean.

Lait VIP O2

Lait VIP O2

This gentle oxygenating and antipollution cleanser is enriched with vitamins A, E, and F to brighten and unify the complexion. This cleanser is ideal for stressed skin or those exposed to pollution or dry climates.

L'eauxygénante Multi-Active Skincare Mist

L'eauxygénante Multi-Active Skincare Mist

This moisturizing mist contains an oxygenating "antipollution" complex, giving new radiance to the complexion. Vitamins A & C and Edelweiss extract combat free radicals.

Need help determining which cleanser is suitable for your skin type? Let our Biologique Recherche skincare experts guide you. Contact us today for a customized consultation.


Lotion P50, the most coveted product, is the pinnacle of Biologique Recherche skincare. Whether administered at home or Lorena Luca Skin and Spa in Raleigh, NC, all treatments start with the P50 ritual. It is applied in the morning and the evening. It provides a gentle exfoliation for the skin, helps control excessive sebum production, offers moisture, and supports the maintenance of the epidermis' acidic pH. Additionally, it effectively prevents and addresses ingrown hairs, making it an excellent choice for both pre and post-shaving skin care. P50 Lotion has a variety of formulations, making this essential product fully tailored to your skin's unique needs.

P50 lotion


Our beloved multi-tasking essential, this product excels at exfoliating, purifying, and cleansing while promoting cell regeneration. Packed with AHA, BHA, PHAs, apple cider vinegar, sulfur, and vitamin B3, it's like "magic in a bottle" that not only revitalizes your skin but also helps maintain its optimal pH balance while providing deep hydration.

P50 1970

P50 1970

This iconic lotion is the original hero of the Biologique Recherche skincare. P50 1970 line can be described as an exfoliating toner that helps skin neutralize PH while making the complexion look brighter and cleaner. P50 1970 uses the original formula with minimal phenol content.



Enriched with vitamins, this exfoliating lotion is best for normal to dry skin that is dull or lacking tone. Beneficial for improving the skin's natural PH balance, it is made with yeast and walnut extract, which contain soothing and toning properties.

Lotion P50V 1970

Lotion P50V 1970

Biologique Recherche's Lotion P50 1970 is a medium-strength all-in-one toner, balancer, and exfoliating lotion enriched with vitamins. This original formula contains minimal phenol content. This lotion is best suited for normal to dry skin.

P50 PIGM 400

P50 PIGM 400

This extension of the P50 lotion line is best for those wishing to reduce pigmentation marks. Made with antioxidant agents such as wasabi extract & vitamin B3 to brighten, this cleanser and exfoliant is best for dull Skin Instants and those targeting a pigmented complexion.

P50W lotion


P50 W is a slightly softer version of the original P50. This exfoliating lotion contains arnica extract, which helps calm the skin. Because of the added Arnica, P50W is excellent for first-time P50 lotion users and those with delicate and reactive skin instants.

Lotion MC 110 N°1

Lotion MC 110 N°1

Lotion MC110 N°1 is a plumping and repairing beauty booster that gently exfoliates even the thinnest skin. Marks and irregular skin are smoothed out, while wrinkles and fine lines fade. The facial contours appear redefined, and the skin is toned and moisturized.

Need help determining which lotion is suitable for your skin type? Let our Biologique Recherche skincare experts guide you. Contact us today for a customized consultation.

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Masks serve as the final layer of products applied before the treatment phase. They boast potent concentrations of active ingredients designed to harmonize and purify the epidermis while preserving the advantages gained from earlier treatments. These formulations are enriched with vital fatty acids, working to restore the skin's proteo-lipidic film following exfoliation, thereby priming the skin for the subsequent products applied during the treatment phase. Unlike other brands, Biologique Recherche masks are involved in the middle of the skincare program and not at the end. This treatment sequence deliberately avoids removing the active ingredients in the treatment stage.

Biomagic Mask

Biomagic Mask

This energizing and pore-tightening mask, formulated with a blend of mineral and terrestrial ingredients, leaves the skin soft, glowing, and purified. It's a BR must-have to use before a big day or night out and is recommended for devitalized or less-toned Skin Instants.

Masque Biosensible

Masque Biosensible

This mask significantly reduces skin sensitivity and gives delicate skin instant relief and comfort. Its soothing and protective active ingredients reduce irritations and help strengthen the skin's natural barrier. It calms and relieves flushing and itching. Skin is left moisturized, soothed, and less reactive to environmental damage.

Masque Bain De Plantes

Masque Bain De Plantes

A deep cleansing and rebalancing mask with 13 active ingredients will gently purify and regulate excess sebum or oil on the face and body without drying or dehydrating. This mask is excellent for acne Skin Instants and leaves the epidermis rebalanced and deeply cleansed.

Masque PIGM 400

Masque PIGM 400

Masque PIGM 400 stands out as an exceptional radiance enhancer. With a potent blend of brightening active ingredients and powerful antioxidants, this formula works wonders for your complexion. It instantly revitalizes and evens out the skin, leaving it noticeably brighter, well-hydrated, and perfected.

Masque VIP 02

Masque VIP 02

This mask is an oxygenating and moisturizing "antipollution" treatment to restore radiance to stressed skin. Enriched with a wealth of moisturizing botanical components, this formula also incorporates the specific Biologique Recherche Oxygenating Complex. This unique blend serves to stimulate and invigorate epidermal regeneration.

Masque Vivant

Masque Vivant

A refreshing and balancing mask produced with yeast, cucumber, and witch hazel purifies the skin and creates a brighter, tighter, mattified, and more toned visage. It is recommended for seborrheic or dull Skin Instants. Skin will appear more youthful and radiant.

Masque Creme Biofixine

Masque Creme Biofixine

This mask reduces the appearance of all types of wrinkles. Use Myorelax Peptide to relax the formation of muscle micro-tension and correct facial expression lines. Its hydrating and antioxidant-active ingredients reduce dehydration lines.

Masque Visolastine

Masque Visolastine

Experience a beamingly bright complexion with each use of this mask. Macadamia and cotton oil act to recover elasticity, while the white clay cleanses the skin without dehydrating it. This mask leaves the skin plump and nourished. It is recommended for all Skin Instants lacking hydration.

Need help determining which mask is suitable for your skin type? Let our Biologique Recherche skincare experts guide you. Contact us today for a customized consultation.

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Quintessential Serums

Quintessential serums represent the epitome of purity within the Biologique Recherche skincare line. These serums treat skin imbalances (dehydrated, devitalized, lined, seborrheic skin, etc.). Quintessential serum may be mixed and used to treat particular face areas.

Collagene Marin serum

Collagene Marin

This Serum tightens the pores and tones the skin. Serum Collagene Marin helps bind water to the skin to plump the epidermis. Not only will your complexion appear youthful and rejuvenated, but this Serum will also form a barrier against impurities to protect it from future damage and loss of moisture.

Dermopore serum


This essential product is crucial for those with dilated pores. It promotes an even complexion, tightens pores, and restores balance. Developed in response to hyper-seborrheic, acneic, and hyper-keratinized Skin Instants, this product refines the skin's texture and leaves a breathtakingly brilliant result.

Extraits Tissulaires serum

Extraits Tissulaires

This intense Serum for problem skin delivers extreme hydration and calmness to intolerant and Sensitive Skin Instants. This SOS product moisturizes the outer layers of the epidermis, creating a luminous glow and preparing the skin to regenerate and strengthen.

Oligo-Proteines Marines serum

Oligo-Proteines Marines

Formulated with a Complex of Marine Oligo Proteins, this serum is meticulously formulated to reduce the visibility of dark circles in the delicate eye area. Its targeted action reduces the bluish undertones, providing an "anti-fatigue" effect that revitalizes and refreshes the skin. The skin is revitalized, and dark circles are plumped for a more rested and luminous look.

Colostrum serum


For extreme cases of dryness, this active Serum brings intense hydration provided by rich and fatty milk proteins. It is best used on mature Skin Instants that lack elasticity and seek moisturization. Serum Colostrum prevents future drying while leaving skin plumped and glowing. Must be kept refrigerated after opening.

Placenta serum


This Serum is ideal for repairing skin and treating post-acne scars. Placenta serum reconstructs and heals skin cells, lightens dark circles, and restores skin suppleness with placenta protein extracts that promote regrowth. Excellent for pigmentation, acne, and any skin imperfections.



This anti-aging and reparative serum is designed to regenerate and hydrate the skin while offering protection. It's an excellent choice for individuals with stressed, dehydrated, and sensitive skin instants. Particularly effective for hydration, this treatment is highly recommended for those with skin concerns that typically arise around the age of 40 and beyond. Calming and nourishing, it enriches the complexion, making it even and desirable.

Collagene Natif

Collagene Natif

Give your skin a silky-soft, glowing appearance with this collagen-based Serum. Collagen is known to tighten the pores and improve the contour of the face.

This Serum can also be used as an eye mask. Separate a cotton pad, lightly saturate each piece with Serum, and leave it on for 15 minutes. It works as a booster and can be great for an instant pick-me-up.

VG Tensil

VG Tensil

The powerful combination of rye and wheat proteins in this serum promotes a firmer and more toned complexion, making it particularly beneficial for individuals experiencing a loss of skin elasticity. Enhanced with botanical serums known for their firming properties, this intensive treatment revitalizes skin tissues and rejuvenates the skin's surface. It stimulates collagen synthesis, making it an excellent choice for mature skin seeking a rejuvenating effect.



Sérum Splénodermine is a potent blend designed to revitalize and strengthen the skin's underlying tissues. Enriched with cellular oligopeptides from spleen extract, this advanced formula works to redefine the contours of the face, making it an ideal choice for those dealing with loss of skin tone. This intensive firming and unifying serum will rejuvenate your complexion, leaving it looking youthful and radiant.

Serum Elastine

Serum Elastine

Harnessing the power of bio-marine ingredients, this serum effectively smoothes the skin's surface, combats the loss of elasticity, and diminishes the visible signs of wrinkles and fine lines.

It suits all skin types and is well tolerated by oily skin instants. It is ideal for treating first wrinkles, expression lines, and the eye and mouth areas.

Sérum A-Glyca

Sérum A-Glyca

Crafted to preserve the integrity of elastin and collagen fibers, this serum emerges as a formidable ally in the battle against aging. Its remarkable properties offer protection and mitigation against skin glycation, potentially reversing two years' worth of glycation effects within a mere two months of consistent use. As a result, wrinkles diminish, skin tone becomes more even, the dermis gains firmness, and the complexion radiates with newfound luminosity.

Serum Iribiol

Serum Iribiol

Designed to address oily, blemish-prone skin, this serum excels in regulating sebum production, refining pores, and thwarting the emergence of potential imperfections. It proves especially beneficial for the T-zone region in combination with skin, unveiling a rejuvenated and healthier radiance. Additionally, it serves as an effective spot treatment for localized concerns.

Serum Iso-Placenta

Serum Iso-Placenta

Serum Iso-Placenta stands as an anti-post blemish mark correction solution dedicated to enhancing skin recovery by refining the skin's microtexture, diminishing redness, and reducing marks. Through its regenerative properties, this serum promotes the restoration of the skin's natural appearance, leaving it revitalized and rejuvenated.

Need help determining which quintessential Serum is suitable for your skin type? Let our Biologique Recherche skincare experts guide you. Contact us today for a customized consultation.

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Targeted Sérums

Biologique Recherche has developed Targeted Serums, a new generation designed to improve specific Skin Instances and temporary imbalances. These serums deliver immediate improvements as well as lasting results. The composition of the Targeted Serums includes active principles that are both physiologically and biotechnologically obtained to attack the causes and consequences of observed skin dysfunctions effectively.

the line of targeted sérums

Sérum Biosensible

A restructuring and soothing serum that strengthens the epidermis and reduces skin sensitivity. Recommended for sensitive Skin Instants.

Sérum PIGM 400

This brightening and dark spot-correcting Serum utilizes six concentrated active ingredients to illuminate the complexion while diminishing dark spots. Additionally, its photo-protective and anti-free radical agents slow the skin's aging with each use.

Sérum Matriciel Visage

It tightens the features, increases the viscoelasticity of the skin tissue, and restores the volume and structure of the face.

Sérum 3R

Sérum 3R combines 12 active ingredients that target the causes and consequences of skin aging. Its exfoliating action allows better cell regeneration while also protecting against free radicals. This Serum is formulated to tighten, hydrate, and plump the skin. It also contains anti-inflammatory active ingredients to assist in the repair of the immune function, which deteriorates with time.

Sérum Erythros

This Serum is specifically for skin instants prone to rosacea and extremely sensitive.
This targeted Serum diffuses redness of the face and the formation of new blood vessels.

Sérum T.E.W.L

This serum serves as a formidable defense against extreme dehydration and provides a protective shield against harsh weather conditions, delivering a wealth of rejuvenating, reparative, and safeguarding active components. It proves especially beneficial for individuals residing in or visiting arid or frigid climates.

Unsure which targeted sérum is suitable for your skin type? Let our Biologique Recherche skincare experts guide you. Contact us today for a customized consultation.


Creams are meticulously applied to the face, neck, and décolleté, delivering a harmonious blend of botanical, biological, and marine elements to nourish the skin. These creams complement the effects of our Quintessential Serums, acting as a shield against external aggressors. With a unique texture that hydrates without leaving behind any greasy residue, they offer ease of application and are enriched with potent active ingredients, ensuring optimal outcomes with just a small amount. Typically, Biologique Recherche Beauty programs encompass two distinct creams tailored for daytime and nighttime use. Our range encompasses three cream variants: Essential, Specific, and Intensive Creams.

the different types of cremes

Crème ISO Placenta

Crème Iso-Placenta provides intense regenerative skincare, explicitly acting on acne-prone skin. It promotes cell regeneration to diminish the appearance of imperfections caused by acne, deeply nourishing skin tissue through biomimicking the properties of the human placenta. Acne scarring is healed, and the skin surface becomes more even with less redness. It is recommended for Skin Instants© showing traces of acne.

Crème PIGM 400

A brightening, pigmentation spot-correcting cream with a pearly finish on the skin. This cream moisturizes while spot-correcting and preventing future pigmentation from developing.

Crème Hydravit's

Brightens dull and stressed complexions in need of moisture. Active ingredients include thermal algae, yeast extract, birch bark extracts, and vitamin C. All are excellent for calming and toning the skin.

Crème Elastine

A silky, nourishing marine-based cream to soften, smooth, and improve skin. This anti-aging treatment prevents wrinkles and restores elasticity. Perfect for Skin Instants who desire anti-aging benefits that occasionally break out. 

Crème Dermopurifiante

Brightens and mattifies the skin. This cream reduces the redness caused by acne and regulates sebum secretion while protecting the epidermis against external aggression. It is recommended for imbalanced seborrheic skin or reactive skin instants.

Crème Splendide

An intensive cream used for instant firmness and glow for skin showing signs of loss and tone. Crème Splendide can also be used as a great neck cream and is intended for more mature skin instants.

Crème Splendide

Crème Grand Millésime

A refreshing, brightening moisturizer for mature skin instants. This crème aids in the prevention of aging signs, enhances skin elasticity, and imparts a rejuvenated, soft feel to the skin, resulting in a radiant complexion.

Crème VIP O2

This protective and brightening day cream defends skin from pollution by incorporating oxygenating agents into its formula. It is particularly significant for those in large cities, smokers, and those with dull and tired skin.

Crème aux Acides de Fruits

Brightens and softens the skin, leaving the skin texture velvety. This product harnesses a unique combination of natural moisturizing factors and a fruit acid complex. It is recommended for devitalized, dull, or stressed skin in a one-month treatment course.

Crème Biofixine

This potent youth-enhancing cream reduces the appearance of fine lines, wrinkles, and skin elasticity. Walnut extracts smooth skin's appearance while grapeseed moisturizes. Studies show a 20% reduction in forehead lines and 22% in smile lines with continued use.

Crème Masque Vernix

Rich in antioxidant peptides and lipids, this cream mimics the protective layer on a baby's skin at birth. It is a repairing and protective treatment ideal for moisture-deficient and stressed skin Instants.

Crème MSR-H

Combats the signs of aging with regenerating and moisturizing action. Designed to address the specific skin challenges associated with menopause, this serum caters to mature skin's unique requirements. Enriched with yam and soya extracts to help balance hormonal changes and shea butter to provide a softening effect, it leaves your skin looking bright, fresh, and radiant.

the different types of crèmes available

Emulsion Gel Biosensible

Its hypoallergenic fluid texture is formulated for naturally sensitive skin, employing highly concentrated moisturizing active ingredients such as essential unsaturated fatty acids and antioxidants. It is recommended for dehydrated, stressed, and Sensitive Skin Instants (not to be used on seborrheic skin).

Emulsion Gel Biosensible S.R.

A gentle lotion designed for individuals with sensitive skin, enlarged pores, and a tendency towards oiliness, this gel reduces blemishes and minimizes overactive skin types for a visibly less oily appearance.

Emulsion Originelle Regerante Face

This cream's formulation combines essential fatty acids and a Botanical Complex to produce a refined, moisturizing emulsion that helps prevent dry skin while calming and soothing the epidermis. It is recommended for delicate and dehydrated Skin Instants.

Gel ADN Silkgen

A light, transparent, non-oily texture that readily absorbs into the skin, bringing a cooling sensation while toning and softening. Firming and protective agents from salmon DNA moisturize while silk extracts smooth the skin. Excellent for frequent travelers, people exposed to arid climates, and for use after plastic surgery or minimally invasive procedures.


This lip product uses shea butter and lanolin to repair the lips, plant-based triglycerides to moisturize, and rosemary oil extract to give the formula antioxidant properties.

Crème VG Derm

Infused with nourishing and hydrating compounds, Crème VG Derm aids in restoring the skin's lipid content and fortifying its inherent barrier to reduce moisture evaporation from the epidermis. This cream ensures sustained and profound hydration for the skin, particularly in the most parched regions. Experience relief from skin tightness as it becomes thoroughly moisturized and enriched with comfort.

Crème Dermo RL

Functioning as a protective barrier for the epidermis, Crème Dermo-RL serves as a comprehensive reparative and regenerative skincare solution. Enriched with lipid-restoring shea butter, cotton oil, Natural Moisturizing Factor (NMF), hydrating hyaluronic acid, and defensive and restorative components, this formula replenishes your skin with essential lipids and fortifies its resilience.

Crème ADN Métamorphique

Crème Métamorphique is expertly crafted to deeply firm and rejuvenate the epidermis. It actively addresses signs of skin aging by reinforcing the underlying tissues, specifically collagen and elastin, and fortifying their structural integrity. Consequently, facial contours are beautifully redefined, providing a noticeable improvement in firmness and resilience.

Crème Verte Espoir A.R.

Crème Verte Espoir A.R. is the perfect solution for addressing facial redness and minimizing the symptoms of rosacea. It effectively targets broken capillaries, visibly diminishing their prominence to reduce both the frequency and intensity of persistent redness. Additionally, it calms sensitive skin reactions that are responsible for occasional red patches. This soothing formula instantly comforts delicate and reactive skin, restoring a uniform and harmonious complexion.

Unsure which Crème is suitable for your skin type? Let our Biologique Recherche skincare experts guide you. Contact us today for a customized consultation.

Eye Creams

the three different types of eye creams

Crème Contoue Yeux et Lèvres Biofixine

A lifting, anti-wrinkle eye cream designed for skin instants affected by the signs of age.

Crème Contour Yeux VIP 02

This eye cream tones and smooths the eye area with its unique oxygenating and moisturizing formula. This formula combines a specific Biologique Recherche Oxygenating Complex and polyunsaturated fatty acids to reduce fine lines and brighten the eye area.

Crème Contour des Yeux Biosensible

A protective, soothing, anti-dark circle cream for the sensitive and devitalized eye contour area. A highly-tolerated, highly effective treatment for the sensitive contour area of eyes, which protects, smooths, and diminishes dark circles and fine lines thanks to its combination of active ingredients.

Need help determining which eye cream is suitable for your skin type? Let our Biologique Recherche skincare experts guide you. Contact us today for a customized consultation.

Finishing Serums

These serums represent the crowning glory of the Biologique Recherche facial care routine. Exuding sophistication and glamour, their unique formulations yield immediate and enduring benefits. They can be applied both beneath and atop creams, bestowing a natural radiance and luminosity to the skin. These precious elixirs feature botanical extracts rich in a variety of vitamins and antioxidants, hyaluronic acid, and potent moisturizing and oxygenating DNA extracts. Serving as a stabilizing force for products utilized during the Treatment Stage, these finishing serums provide an excellent makeup base. They prove ideal for daily use and special occasions alike, extending and safeguarding the effects of Biologique Recherche skincare products.

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the whole line of serum products

Le Grand Sérum

This formula contains 27 active ingredients for mature skin to strengthen the skin's natural defense, leaving your skin luminous and plump.

Sérum Yall~O2

Rich in hyaluronic acid and marine collagen, this Serum fights dehydration and aging by reducing the size and depth of lines and wrinkles. The richest of all serums, this product is best for Mature Skin infants needing hydration and plumping.

Sérum Grand Millésime: Elixir Hors du Temps

An elixir of youth, this Serum brings moisture and suppleness to help repair signs of aging. Skin appears visibly smoother and plumper. Your complexion is left rested and radiant.

Silk Plus: Elixir de Douceur

With active ingredients making up more than 40% of this rich Serum, skin is guaranteed to hydrate, regenerate and repair. Silk Plus finishing Serum supports sensitive skin, leaving a silky sensation. It is excellent as a makeup base or for use after shaving.

Fluide VIP02

This Serum is an anti-pollutant for stressed skin, especially for people who live in big cities. This finishing Serum helps increase oxygen concentration on the skin's surface and diminishes red blemishes while hydrating the top layers of the epidermis and brightening the complexion. 

Complexe Royale

Soothe and revitalize skin with cucumber and witch hazel for an energized finish. This Serum will keep skin moist and hydrated all day long.

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Why choose Lorena Luca Med + Spa?

Experience the ultimate skincare luxury and transformation by choosing Lorena Luca Med + Spa. We are dedicated to helping you achieve the healthy, radiant skin you desire, and our selection of Biologique Recherche products assists in that process. Elevate your skincare regimen with these exceptional formulations and discover their rejuvenating power. From personalized consultations to tailored product recommendations, our team is here to guide you on your journey to achieving radiant and youthful skin. Embrace the transformative potential of Biologique Recherche products and schedule your consultation with us today.

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